Awake, awake, stand up, O Jerusalem, which hast drunk at the hand of the LORD the cup of his fury; thou hast drunken the dregs of the cup of trembling, and wrung them out.
God, having awoke for the comfort of his people, here calls upon them to awake, as afterwards, Isa 52:1. It is a call to awake not so much out of the sleep of sin (though that also is necessary in order to their being ready for deliverance) as out of the stupor of despair.
Commenting on Isaiah 51:17-23
Awake, awake, stand up, O Jerusalem,.... As persons out of a sleep, or out of a stupor, or even out of the sleep of death; for this respects a more glorious state of the church, the Jerusalem, the mother of us all, after great afflictions; and especially if it respects the more glorious state of all on earth, signified by the New Jerusalem, that will...
Awake, awake, stand up, O Jerusalem, &c.-- (Isa 52:1). drunk--Jehovah's wrath is compared to an intoxicating draught because it confounds the sufferer under it, and makes him fall (Job 21:20; Psa 60:3; Psa 75:8; Jer 25:15-16; Jer 49:12; Zac 12:2; Rev 14:10); ("poured out without mixture"; rather, "the pure wine juice mixed with intoxicating drugs"). of trembling--which produced trembling or intoxication. wrung . . .