See, your house is left to you desolate.
They boasted of the temple as God's invincible fortress, convinced He was bound to that place and could not abandon it. But Christ declares it their house now, not His, He has withdrawn His presence because they drove Him away by their crimes. The temple's destruction is God's terrible judgment: the very place He adorned with such magnificence, ordained to fall at Christ's coming, was instead razed to the ground and left to infamy forever because of the people's wickedness.
AI summary
Their house becomes desolate the moment Christ departs, when He is crucified, they lose His presence entirely. They will never see Him again until the distant day when Israel is converted and confesses Him willingly; until then, though they may be forced to acknowledge Him as Lord, they will never say those blessed words in faith and holy reverence, but only under compulsion.
AI summary
Verse 38. Your house. The temple. The house of worship of the Jews. The chief ornament of Jerusalem. Desolate. About to be desolate, or destroyed. To be forsaken as a place of worship, and delivered into the hands of the Romans, and destroyed. and following. (y) "desolate"